Geohazard Caused by Groundwater in Urban Underground Excavation

This paper addresses the important role of water click here in geohazard and failure in urban underground excavation.These so-called underground water-related hazards, such as leakage of the tunnel eye due to launching and docking of the shield, failure of the cross-passage excavation, and failure of the retaining wall caused by water ingress for d

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Arsinothricin Inhibits Plasmodium falciparum Proliferation in Blood and Blocks Parasite Transmission to Mosquitoes

Malaria, caused by Plasmodium protozoal parasites, remains a leading cause of morbidity and mortality.The Plasmodium parasite has a complex life cycle, with asexual and sexual forms in humans and Anopheles mosquitoes.Most antimalarials target only the symptomatic asexual blood stage.However, to ensure malaria eradication, new drugs with efficacy at

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Cofilin-1, LIMK1 and SSH1 are differentially expressed in locally advanced colorectal cancer and according to consensus molecular subtypes

Abstract Background Colorectal cancer (CRC) is among the deadliest cancers, wherein early dissemination of tumor cells, and consequently, metastasis formation, are the main causes of mortality and poor prognosis.Cofilin-1 (CFL-1) and its modulators, LIMK1/SSH1, play key roles in mediating the invasiveness by driving actin cytoskeleton reorganizatio

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